Prenatal chromosome analysis Article

Lisgar, F, Gertner, M, Cherry, S et al. (1970). Prenatal chromosome analysis . NATURE, 225(5229), 280-281. 10.1038/225280a0

cited authors

  • Lisgar, F; Gertner, M; Cherry, S; Hsu, LY; Hirschhorn, K



  • CHROMOSOME analysis can be performed on fibroblasts cultured from amniotic fluid1-3. This is the basis of a technique for the intrauterine detection of chromosomal aberrations in the foetuses of women who are known to have a high risk of producing abnormal offspring. Valenti et al.1, for example, reported the intrauterine detection of trisomy 21 in amniotic fluid cell cultures and they subsequently performed a therapeutic abortion. The pathological findings on the foetus confirmed the diagnosis. © 1970 Nature Publishing Group.

publication date

  • December 1, 1970

published in

Digital Object Identifier (DOI)

start page

  • 280

end page

  • 281


  • 225


  • 5229