Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders Book Chapter

Hauser, KF, El-Hage, N, Buch, S et al. (2006). Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders . 10.1093/acprof:oso/9780195183139.003.0022

cited authors

  • Hauser, KF; El-Hage, N; Buch, S; Barnes, GN; Bada, HS; Pauly, JR

authors

abstract

  • Considerable evidence suggests that drugs with abuse liability disrupt development by affecting the production of new neurons and glia. The effects of drug abuse are not limited to a particular cell type, germinal zone, or stage of development, but rather uniquely affect individual neuronal and glial precursor types with various germinal zones. Germinal zones are targeted to varying degrees by most substance with abuse liability. This chapter discusses the effects of opiates and nicotine on the genesis of neural cells.

publication date

  • May 25, 2006