Insulin Resistance and Cardiovascular Disease Risk in Black People of the African Diaspora Review

Gaillard, T. (2010). Insulin Resistance and Cardiovascular Disease Risk in Black People of the African Diaspora . Current Cardiovascular Risk Reports, 4(3), 186-194. 10.1007/s12170-010-0092-x

cited authors

  • Gaillard, T

abstract

  • Insulin resistance plays a pivotal role in the development of cardiovascular disease (CVD) in whites. Insulin resistance syndrome includes a constellation of diseases such as hyperglycemia, obesity, hypertension, hypertriglyceridemia, and low high-density lipoprotein cholesterol. Black People of the African Diaspora (PAD) have greater rates of insulin resistance than whites, but the association of insulin resistance to CVD in black PAD is controversial. Moreover, among black PAD, the relationship of insulin resistance with coronary artery disease varies depending on geographic location. In general, in black PAD there is emerging evidence that indicates increases in the incidence of CVD mortality and morbidity are attributable predominately to hypertension and lifestyle. Overall, the higher CVD in black PAD occurs even though their characteristic lipid/lipoprotein profile is antiatherogenic. This review provides a critical examination of the role of insulin resistance in the development of CVD in black PAD and compares and contrasts insulin resistance, the lipid/lipoprotein profile, and blood pressure in black PAD and whites. © 2010 Springer Science+Business Media, LLC.

authors

publication date

  • March 19, 2010

published in

Digital Object Identifier (DOI)

start page

  • 186

end page

  • 194

volume

  • 4

issue

  • 3