Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA Article

Skarzynski, T, Kim, DH, Lees, WJ et al. (1998). Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA . BIOCHEMISTRY, 37(8), 2572-2577. 10.1021/bi9722608

Industry Collaboration International Collaboration

cited authors

  • Skarzynski, T; Kim, DH; Lees, WJ; Walsh, CT; Duncan, K

sustainable development goals

authors

publication date

  • February 24, 1998

published in

keywords

  • (E)-3-FLUOROPHOSPHOENOLPYRUVATE
  • (Z)-3-FLUOROPHOSPHOENOLPYRUVATE
  • ADDUCT
  • ANTIBIOTIC FOSFOMYCIN
  • Biochemistry & Molecular Biology
  • CYS115
  • EPSP SYNTHASE
  • INACTIVATION
  • Life Sciences & Biomedicine
  • REFINEMENT
  • SYNTHETASE
  • Science & Technology
  • TARGET

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 2572

end page

  • 2577

volume

  • 37

issue

  • 8