In a meshfree system, a geometric model of a domain neither conforms to, nor is restricted by a spatial discretization. Such systems for engineering analysis offer numerous advantages over the systems that are based on traditional mesh-based methods, but they also require radical approaches to enforcing boundary conditions and novel computational tools for differentiation, integration, and visualization of fields and solutions. We show that all of these challenges can be overcome, and describe SAGE (Semi-Analytic Geometry Engine) - a successful system specifically intended for meshfree engineering analysis. Our approach and individual modules are based on Rvachev's Function Method (RFM) but the described techniques, algorithms, and software are applicable to all mesh-based and meshfree methods and have broad use beyond solutions of boundary value problems.