Human T-lymphotropic Virus 1 (HTLV-1) infection - dermatological implications Article

Amano, M, Setoyama, M, Grant, A et al. (2011). Human T-lymphotropic Virus 1 (HTLV-1) infection - dermatological implications . INTERNATIONAL JOURNAL OF DERMATOLOGY, 50(8), 915-920. 10.1111/j.1365-4632.2011.04882.x

cited authors

  • Amano, M; Setoyama, M; Grant, A; Kerdel, FA

authors

abstract

  • Human T-lymphotropic virus type 1 (HTLV-1) is a type C retrovirus primarily endemic to Japan, Central and South America, the Middle East, regions of Africa, and the Caribbean. Currently, an estimated 10-20 million people worldwide are infected with this virus. Although the majority of infected individuals remain asymptomatic, HTLV-1 is the causative agent of a number of disorders, notably adult T-cell leukemia/lymphoma (ATLL) and a progressive demyelinating neurological disorder, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). In addition to ATLL and HAM/TSP, HTLV-1 has been associated with a spectrum of skin disorders, such as infective dermatitis associated with HTLV-1, crusted scabies, and leprosy. The understanding of the interaction between virus and host response has improved markedly, but there are still few treatment options. © 2011 The International Society of Dermatology.

publication date

  • August 1, 2011

published in

Digital Object Identifier (DOI)

start page

  • 915

end page

  • 920

volume

  • 50

issue

  • 8