Clinical trials targeting lung cancer with active immunotherapy: The scope of vaccines Article

Raez, LE, Santos, ES, Mudad, R et al. (2005). Clinical trials targeting lung cancer with active immunotherapy: The scope of vaccines . EXPERT REVIEW OF ANTICANCER THERAPY, 5(4), 635-644. 10.1586/14737140.5.4.635

cited authors

  • Raez, LE; Santos, ES; Mudad, R; Podack, ER

authors

abstract

  • Successful active immunotherapy is expected to be specific and nontoxic. Until now, the success of immunotherapy in cancer has been sporadic and unpredictable. This has been attributable in part to the lack of a full understanding of the mechanistic underpinnings of immune regulation. Furthermore, the lack of systematic success of immunotherapy, as argued in this review, stems from failing to effectively target tumors such as non-small cell lung cancer. In this review, the rationale and design for induction of immunity to non-small cell lung cancer and clinical trials of the most important lung cancer vaccines in development are discussed. © 2005 Future Drugs Ltd.

publication date

  • August 1, 2005

published in

Digital Object Identifier (DOI)

start page

  • 635

end page

  • 644

volume

  • 5

issue

  • 4