Estimation of a model of cumulative pregnancy following infertility therapy Article

Guzick, DS, Rock, JA. (1981). Estimation of a model of cumulative pregnancy following infertility therapy . AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 140(5), 573-578. 10.1016/0002-9378(81)90235-0

cited authors

  • Guzick, DS; Rock, JA

authors

abstract

  • Life-table estimation of cumulative pregnancy curves following infertility therapy is an important tool for evaluating the effectiveness of therapy. However, a satisfactory method for summarizing an entire cumulative pregnancy curve in terms of a small number of clinically useful parameters is currently lacking. In the present paper, a model is developed in which cumulative pregnancy is expressed as a function of two parameters: the cure rate and the instantaneous probability of pregnancy among those cured. This model is applied to data on endometriosis and polycystic ovary syndrome, and the resulting predicted cumulative pregnancy curves almost perfectly follow the observed data. © 1981.

publication date

  • July 1, 1981

published in

Digital Object Identifier (DOI)

start page

  • 573

end page

  • 578

volume

  • 140

issue

  • 5