Danazol in the treatment of recurrent or persistent endometriosis: A preliminary report
Article
Hernandez, E, Sapp, K, Rock, JA. (1981). Danazol in the treatment of recurrent or persistent endometriosis: A preliminary report
. Infertility, 4(1), 29-35.
Hernandez, E, Sapp, K, Rock, JA. (1981). Danazol in the treatment of recurrent or persistent endometriosis: A preliminary report
. Infertility, 4(1), 29-35.
Fifteen patients with documented recurrent or persistent endometriosis were treated with 800 mg of danazol per day for 6 months. All of them were infertile and following therapy, 3 patients conceived (20%), but only one of them resulted in a living child. Danazol gave complete relief of symptoms in 9 of 10 patients with recurrent dysmenorrhea. One woman developed pain 6 months after completion of therapy. Since pregnancy rates following a second operation for endometriosis are discouraging, this non-operative form of treatment warrants additional trials.