Estrogen, mitochondria, and growth of cancer and non-cancer cells

Estrogen, mitochondria, and growth of cancer and non-cancer cells Article

Felty, Q, Roy, D. (2005). Estrogen, mitochondria, and growth of cancer and non-cancer cells . 4 10.1186/1477-3163-4-1

In this review, we discuss estrogen actions on mitochondrial function and the possible implications on cell growth. Mitochondria are important targets of estrogen action. Therefore, an in-depth analysis of interaction between estrogen and mitochondria; and mitochondrial signaling to nucleus are pertinent to the development of new therapy strategies for the treatment of estrogen-dependent diseases related to mitochondrial disorders, including cancer. © 2005 Felty and Roy; licensee BioMed Central Ltd.