Plasma lipid profile, lipid peroxidation and antioxidant status in preeclamptic and uncomplicated pregnancies in Bangladesh
Article
Howlader, ZH, Kabir, Y, Khan, TA et al. (2007). Plasma lipid profile, lipid peroxidation and antioxidant status in preeclamptic and uncomplicated pregnancies in Bangladesh
. 7(8), 1276-1282. 10.3923/jms.2007.1276.1282
Howlader, ZH, Kabir, Y, Khan, TA et al. (2007). Plasma lipid profile, lipid peroxidation and antioxidant status in preeclamptic and uncomplicated pregnancies in Bangladesh
. 7(8), 1276-1282. 10.3923/jms.2007.1276.1282
To investigate the changes in plasma lipid profile, lipid peroxidation and antioxidant status in Bangladeshi pregnant women and their potential involvement in the pathophysiology of preeclampsia, we performed a case-control study consisting of randomly selected women (20-30 years) with preeclampsia (PE, n = 25) as compared to uncomplicated normal pregnant (UP, n = 22) and nonpregnant (NC, n = 25) women. The study was conducted in the Clinical Biochemistry Laboratory of Dhaka University. Serum lipid profile, thiobarbituric acid reactive substances (TBARS), lipid hydroperoxide (LHP), Total Antioxidant Status (TAS) and vitamin C levels were measured using standard methods. Serum total cholesterol levels of PE and UP groups were significantly higher (p<0.001) compared to Nonpregnant Control (NC) group. But there was no significant difference between the total cholesterol levels of PE and UP groups. Serum TG level of PE group was significantly higher compared to UP (p<0.01) and NC (
