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Yoshinaga, Masafumi
Positions
Assistant Professor
,
Cellular Biology and Pharmacology
,
Herbert Wertheim College of Medicine
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Scholarly & Creative Works
Research
Identifiers
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Scholarly & Creative Works
Patents issued
Arsinothricin and Methods of Treating Infections Using Arsinothricin
Patent
Synthesis of the Organoarsenical Antibiotic Arsinothricin and Derivatives Thereof
Patent
Synthesis of the Organoarsenical Antibiotic Arsinothricin and Derivatives Thereof
Patent
selected scholarly works & creative activities
Article
2023
Arsinothricin Inhibits
Plasmodium falciparum
Proliferation in Blood and Blocks Parasite Transmission to Mosquitoes
Full Text via DOI:
10.3390/microorganisms11051195
Web of Science:
000998111500001
2023
The ArsQ permease and transport of the antibiotic arsinothricin
.
MOLECULAR MICROBIOLOGY
. 119:505-514.
Full Text via DOI:
10.1111/mmi.15045
Web of Science:
000940321700001
2023
Arsenic and Mercury Distribution in an Aquatic Food Chain: Importance of Femtoplankton and Picoplankton Filtration Fractions
.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
. 42:225-241.
Full Text via DOI:
10.1002/etc.5516
Web of Science:
000894835200001
2022
Arsenic Metabolism, Toxicity and Accumulation in the White Button Mushroom
Agaricus bisporus
Full Text via DOI:
10.3390/toxics10100554
Web of Science:
000873622600001
2022
Selective Methylation by an ArsM S-Adenosylmethionine Methyltransferase from
Burkholderia
gladioli
GSRB05 Enhances Antibiotic Production
.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
.
Full Text via DOI:
10.1021/acs.est.2c04324
Web of Science:
000859998200001
2022
The ArsI C-As lyase: Elucidating the catalytic mechanism of degradation of organoarsenicals
.
JOURNAL OF INORGANIC BIOCHEMISTRY
. 232.
Full Text via DOI:
10.1016/j.jinorgbio.2022.111836
Web of Science:
000795090100004
2022
An ArsRC fusion protein enhances arsenate sensing and detoxification
.
ENVIRONMENTAL MICROBIOLOGY
. 24:1977-1987.
Full Text via DOI:
10.1111/1462-2920.15957
Web of Science:
000763772300001
2021
Chemical synthesis of the organoarsenical antibiotic arsinothricin
Full Text via DOI:
10.1039/d1ra06770b
Web of Science:
000714163200001
2021
Identification of the Biosynthetic Gene Cluster for the Organoarsenical Antibiotic Arsinothricin
Full Text via DOI:
10.1128/Spectrum.00502-21
Web of Science:
000703076500092
2021
Selenite Inhibits Notch Signaling in Cells and Mice
Full Text via DOI:
10.3390/ijms22052518
Web of Science:
000628293900001
2020
Lithium promotes malignant transformation of nontumorigenic cells
in vitro
.
SCIENCE OF THE TOTAL ENVIRONMENT
. 744.
Full Text via DOI:
10.1016/j.scitotenv.2020.140830
Web of Science:
000573748900014
2020
Semisynthesis of the Organoarsenical Antibiotic Arsinothricin
.
JOURNAL OF NATURAL PRODUCTS
. 83:2809-2813.
Full Text via DOI:
10.1021/acs.jnatprod.0c00522
Web of Science:
000575848000032
2020
Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA
.
CHEMOSPHERE
. 254.
Full Text via DOI:
10.1016/j.chemosphere.2020.126911
Web of Science:
000538150400126
2020
Removal of As(III) from Water Using the Adsorptive and Photocatalytic Properties of Humic Acid-Coated Magnetite Nanoparticles
Full Text via DOI:
10.3390/nano10081604
Web of Science:
000564761800001
2019
Reduction of Organoarsenical Herbicides and Antimicrobial Growth Promoters by the Legume Symbiont
Sinorhizobium meliloti
.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
. 53:13648-13656.
Full Text via DOI:
10.1021/acs.est.9b04026
Web of Science:
000500838900011
2019
Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic
Full Text via DOI:
10.1038/s42003-019-0365-y
Web of Science:
000465423400001
2019
The antibiotic action of methylarsenite is an emergent property of microbial communities
.
MOLECULAR MICROBIOLOGY
. 111:487-494.
Full Text via DOI:
10.1111/mmi.14169
Web of Science:
000458286600012
2018
A disadvantageous effect of adsorption of barium by melanin on transforming activity
.
CHEMOSPHERE
. 210:384-391.
Full Text via DOI:
10.1016/j.chemosphere.2018.07.022
Web of Science:
000447112600044
2018
Hepatic ZIP8 deficiency is associated with disrupted selenium homeostasis, liver pathology, and tumor formation
Full Text via DOI:
10.1152/ajpgi.00165.2018
Web of Science:
000447163500014
2018
Directed Evolution of
Saccharomyces cerevisiae
for Increased Selenium Accumulation
Full Text via DOI:
10.3390/microorganisms6030081
Web of Science:
000446334200026
2018
A comprehensive study including monitoring, assessment of health effects and development of a remediation method for chromium pollution
.
CHEMOSPHERE
. 201:667-675.
Full Text via DOI:
10.1016/j.chemosphere.2018.03.026
Web of Science:
000430895300074
2017
Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro
Full Text via DOI:
10.1007/s12640-017-9783-0
Web of Science:
000410949900013
2017
Biochemical Characterization of Arsl: A Novel C-As Lyase for Degradation of Environmental Organoarsenicals
.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
. 51:11115-11125.
Full Text via DOI:
10.1021/acs.est.7b03180
Web of Science:
000412716500023
2016
Uranium in well drinking water of Kabul, Afghanistan and its effective, low-cost depuration using Mg-Fe based hydrotalcite-like compounds
.
CHEMOSPHERE
. 165:27-32.
Full Text via DOI:
10.1016/j.chemosphere.2016.08.124
Web of Science:
000386402200004
2016
Structure of the Arsl C-As Lyase: Insights into the Mechanism of Degradation of Organoarsenical Herbicides and Growth Promoters
.
JOURNAL OF MOLECULAR BIOLOGY
. 428:2462-2473.
Full Text via DOI:
10.1016/j.jmb.2016.04.022
Web of Science:
000377733200016
2016
Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance
.
MOLECULAR MICROBIOLOGY
. 100:945-953.
Full Text via DOI:
10.1111/mmi.13371
Web of Science:
000379687100004
2016
Vanadium-Binding Ability of Nucleoside Diphosphate Kinasefrom the Vanadium-Rich Fan Worm, Pseudopotamilla occelata
Full Text via DOI:
10.2108/zs150188
Web of Science:
000377482600006
2015
Draft Genome Sequence of Burkholderia sp. MR1, a Methylarsenate-Reducing Bacterial Isolate from Florida Golf Course Soil
Full Text via DOI:
10.1128/genomeA.00608-15
Web of Science:
000460631200185
2014
Crystallization and preliminary X-ray crystallographic studies of the ArsI C-As lyase from
Thermomonospora curvata
Full Text via DOI:
10.1107/S2053230X14008814
Web of Science:
000337062500015
2014
A C•As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
. 111:7701-7706.
Full Text via DOI:
10.1073/pnas.1403057111
Web of Science:
000336411300050
2012
Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in
Danio rerio
.
TOXICOLOGY AND APPLIED PHARMACOLOGY
. 262:185-193.
Full Text via DOI:
10.1016/j.taap.2012.04.035
Web of Science:
000305845400010
2011
Pentavalent Arsenate Transport by Zebrafish Phosphate Transporter NaPi-IIb1
.
ZEBRAFISH
. 8:125-131.
Full Text via DOI:
10.1089/zeb.2011.0701
Web of Science:
000295031900004
2011
Demethylation of methylarsonic acid by a microbial community
.
ENVIRONMENTAL MICROBIOLOGY
. 13:1205-1215.
Full Text via DOI:
10.1111/j.1462-2920.2010.02420.x
Web of Science:
000289798600008
2009
Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
. 106:15956-15960.
Full Text via DOI:
10.1073/pnas.0908108106
Web of Science:
000269806600080
2007
Metal binding ability of glutathione transferases conserved between two animal species, the vanadium-rich ascidian
Ascidia sydneiensis samea
and the schistosome
Schistosoma japonicum
.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
. 1770:1413-1418.
Full Text via DOI:
10.1016/j.bbagen.2007.05.007
Web of Science:
000249511200018
2006
Glutathione transferases with vanadium-binding activity isolated from the vanadium-rich ascidian
Ascidia sydneiensis
samea
.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
. 1760:495-503.
Full Text via DOI:
10.1016/j.bbagen.2006.01.008
Web of Science:
000236494000024
1999
Hemorrhagic panesophagitis after acute organophosphorus poisoning
.
GASTROINTESTINAL ENDOSCOPY
. 49:642-643.
Full Text via DOI:
10.1016/S0016-5107(99)70397-4
Web of Science:
000080231100018
1995
EVALUATION OF THE SENSITIVITY OF AN IMMUNOCHEMICAL FECAL OCCULT BLOOD-TEST FOR COLORECTAL NEOPLASIA
.
AMERICAN JOURNAL OF GASTROENTEROLOGY
. 90:1076-1079.
Web of Science:
A1995RH99700010
Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents
.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
. 28:64-68.
Full Text via DOI:
10.1038/jes.2016.70
Web of Science:
000419843700008
DIRECT CONTRACTILE EFFECT OF ENDOTHELIN-1 ON ISOLATED CIRCULAR SMOOTH-MUSCLE CELLS OF GUINEA-PIG CECUM
Full Text via DOI:
10.1159/000201216
Web of Science:
A1995QE44200003
Book Chapter
2014
Arsenic biotransformations
. 309-311.
Full Text via DOI:
10.1201/b16767-118
Conference
2018
ArsI, a C-As lyase for degradation of environmental organoarsenicals
.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
.
Web of Science:
000447609106239
2018
Arsinothricin: a novel arsenic-containing antibiotic
. 319-321.
Web of Science:
000507999600126
2014
Enzymes of arsenic biotransformation
.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
. S178-S178.
Web of Science:
000332835300120
2014
Arsenic biotransformations: The cycle of arsenic methylation and demethylation
. 309-311.
2012
Pathways of arsenic biotransformations: The arsenic methylation cycle
. 185-188.
Web of Science:
000393139700065
2007
Genes and Proteins Involved in Vanadium Accumulation by Ascidians
.
ACS SYMPOSIUM SERIES
. 264-+.
Web of Science:
000269059400020
2006
Characterization of the AsGSTs, vanadium-binding glutathione transferases isolated from the vanadium-rich ascidian Ascidia sydneiensis samea
. 1196-1196.
Web of Science:
000245170200400
2006
INOR 452-Genes and proteins involved in vanadium accumulation by ascidians
.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
.
Web of Science:
000207781606459
2006
INOR 824-Characterization of the AsGSTs, vanadium-binding glutathione transferases isolated from the vanadium-rich ascidian Ascidia sydneiensis samea
.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
.
Web of Science:
000207781606460
2005
Glutathione S-transferase having vanadium-binding activity isolated from a vanadium-accumulating ascidian, Ascidia sydneiensis samea
. 1493-1493.
Web of Science:
000237653101475
2004
Screening of novel vanadium binding proteins from Ascidia sydneiensis samea
. 1326-1326.
Web of Science:
000237651300559
Letter
2016
Reply to the commentary "To Gorelenkova Miller and Mieyal (2015): Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases" by Mieyal JJ
.
ARCHIVES OF TOXICOLOGY
. 1523-1524.
Full Text via DOI:
10.1007/s00204-016-1705-z
Web of Science:
000376409100021
1996
Some aspects of the screening for colorectal cancer - Reply
.
AMERICAN JOURNAL OF GASTROENTEROLOGY
. 618-618.
Web of Science:
A1996TZ00700046
Note
1994
CYTOMEGALOVIRUS-ASSOCIATED GASTRIC ULCERATIONS IN A NORMAL HOST
.
AMERICAN JOURNAL OF GASTROENTEROLOGY
. 448-449.
Web of Science:
A1994NA38300032
Other Scholarly Work
2018
Hepatic ZIP8 deficiency is associated with disrupted selenium homeostasis, liver pathology, and tumor formation (vol 315, pg G569, 2018)
. G908-G908.
Full Text via DOI:
10.1152/ajpgi.zh3-7539-corr.2018
Web of Science:
000451199900025
2016
Commentary to Gorelenkova Miller and Mieyal (2015): sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases
.
ARCHIVES OF TOXICOLOGY
. 1017-1018.
Full Text via DOI:
10.1007/s00204-016-1662-6
Web of Science:
000372427900023
Preprint
2022
The Arsi C-As Lyase: Elucidating the Catalytic Mechanism of Degradation of Organoarsenicals
Full Text via DOI:
10.2139/ssrn.4053474
Review
2023
Arsenic in medicine: past, present and future
.
BIOMETALS
. 283-301.
Full Text via DOI:
10.1007/s10534-022-00371-y
Web of Science:
000758979200001
2022
The enigma of environmental organoarsenicals
.
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
. 3835-3862.
Full Text via DOI:
10.1080/10643389.2021.1947678
Web of Science:
000674789900001
2021
Antimicrobial Activity of Metals and Metalloids
. 175-197.
Full Text via DOI:
10.1146/annurev-micro-032921-123231
Web of Science:
000705971000009
2014
Earth Abides Arsenic Biotransformations
. 443-+.
Full Text via DOI:
10.1146/annurev-earth-060313-054942
Web of Science:
000348436700020
Research
principal investigator on
Molecular mechanisms of aerobic degradation of environmental organoarsenical herbicides and growth promoters by a bacterial community
awarded by
National Science Foundation
2018 - 2023
Pathways and molecular mechanisms of activation/synthesis and detoxification of organoarsenic antibiotics
awarded by
DrHerbert & Nicole Wertheim Family Found
2017 - 2019
Molecular mechanisms of degradation of environmental organoarsenical herbicides and growth promoters
awarded by
DrHerbert & Nicole Wertheim Family Found
2014 - 2015
co-principal investigator on
Grant
Mechanisms of arsenic transport and biotransformations
awarded by
General Medical Sciences
2020 - 2025
Identifiers
ORCID iD
https://orcid.org/0000-0002-7243-1761
(confirmed)
visualizations
Co-author Network
Co-investigator Network
Map of Science
publication subject areas
Astronomy & Astrophysics
Biochemistry & Molecular Biology
Chemistry
Developmental Biology
Engineering
Environmental Sciences & Ecology
Gastroenterology & Hepatology
Microbiology
Pharmacology & Pharmacy
Physiology
Science & Technology - Other Topics
Toxicology
Zoology
Citation index-derived subject areas the researcher has published in