Tempest, Helen

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Tempest, Helen

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selected scholarly works & creative activities

Article
- 2020
  
  A case for written examinations in undergraduate medical education: experiences with modified essay examinations. ASSESSMENT & EVALUATION IN HIGHER EDUCATION. 45:926-939.
  Full Text via DOI: 10.1080/02602938.2020.1714543 Web of Science: 000509187200001
- 2019
  
  Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay
  Full Text via DOI: 10.3390/ijms20236072 Web of Science: 000504428300254
- 2019
  
  Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes
  Full Text via DOI: 10.3390/ijms20205112 Web of Science: 000498822800144
- 2019
  
  Human Sperm Chromosomes: To Form Hairpin-Loops, Or Not to Form Hairpin-Loops, That Is the Question. GENES. 10.
  Full Text via DOI: 10.3390/genes10070504 Web of Science: 000478636700008
- 2018
  
  The Educational Effects of a Summative Diagnostic Reasoning Examination Among Second-Year Medical Students
  Full Text via DOI: 10.1007/s40670-018-0610-x
- 2017
  
  A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions. SCIENTIFIC REPORTS. 7.
  Full Text via DOI: 10.1038/srep41585 Web of Science: 000392956200001
- 2016
  
  Design of a Platform to Discuss Ethical Considerations of Preimplantation Genetic Diagnosis: a Case for Integration of Ethics in Foundational Science Medical Curriculum
  Full Text via DOI: 10.1007/s40670-016-0234-y
- 2015
  
  Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal. MOLECULAR CYTOGENETICS. 8.
  Full Text via DOI: 10.1186/s13039-015-0146-3 Web of Science: 000357252900001
- 2015
  
  Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B. PLOS ONE. 10.
  Full Text via DOI: 10.1371/journal.pone.0118886 Web of Science: 000351275700029
- 2015
  
  Meiotic Nondisjunction: Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa
  Full Text via DOI: 10.1007/978-3-319-18881-2_1 Web of Science: 000361813200002
- 2012
  
  Hierarchical radial and polar organisation of chromosomes in human sperm. CHROMOSOME RESEARCH. 20:875-887.
  Full Text via DOI: 10.1007/s10577-012-9323-y Web of Science: 000312632500006
- 2011
  
  Meiotic recombination and male infertility: from basic science to clinical reality?. ASIAN JOURNAL OF ANDROLOGY. 13:212-218.
  Full Text via DOI: 10.1038/aja.2011.1 Web of Science: 000288074400018
- 2010
  
  Scoring of sperm chromosomal abnormalities by manual and automated approaches: qualitative and quantitative comparisons. ASIAN JOURNAL OF ANDROLOGY. 12:257-262.
  Full Text via DOI: 10.1038/aja.2009.85 Web of Science: 000275109700017
- 2009
  
  Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis. BMC GENOMICS. 10.
  Full Text via DOI: 10.1186/1471-2164-10-357 Web of Science: 000269510400001
- 2009
  
  Cytogenetic risks in chromosomally normal infertile men. CURRENT OPINION IN OBSTETRICS & GYNECOLOGY. 21:223-227.
  Full Text via DOI: 10.1097/GCO.0b013e32832947c2 Web of Science: 000266576400004
- 2009
  
  Quantum dots as new-generation fluorochromes for FISH: an appraisal. CHROMOSOME RESEARCH. 17:519-530.
  Full Text via DOI: 10.1007/s10577-009-9051-0 Web of Science: 000269055300009
- 2009
  
  The use of an e-learning constructivist solution in workplace learning. INTERNATIONAL JOURNAL OF INDUSTRIAL ERGONOMICS. 39:548-553.
  Full Text via DOI: 10.1016/j.ergon.2008.10.019
- 2009
  
  Intra-individual and inter-individual variations in sperm aneuploidy frequencies in normal men. FERTILITY AND STERILITY. 91:185-192.
  Full Text via DOI: 10.1016/j.fertnstert.2007.11.002 Web of Science: 000262396700027
- 2008
  
  Whole genome comparative studies between chicken and turkey and their implications for avian genome evolution. BMC GENOMICS. 9.
  Full Text via DOI: 10.1186/1471-2164-9-168 Web of Science: 000255709200001
- 2008
  
  Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients. HUMAN REPRODUCTION. 23:251-258.
  Full Text via DOI: 10.1093/humrep/dem389 Web of Science: 000252544300004
- 2008
  
  The role of sperm aneuploidy as a predictor of the success of intracytoplasmic sperm injection?. HUMAN REPRODUCTION. 23:240-250.
  Full Text via DOI: 10.1093/humrep/dem395 Web of Science: 000252544300003
- 2008
  
  Plants Used in Chinese Medicine for the Treatment of Male Infertility Possess Antioxidant and Anti-Oestrogenic Activity. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 54:185-195.
  Full Text via DOI: 10.1080/19396360802379073 Web of Science: 000260230900003
- 2007
  
  Practicable approaches to facilitate rapid and accurate molecular cytogenetic mapping in birds and mammals
  Full Text via DOI: 10.1159/000103163 Web of Science: 000249980800006
- 2007
  
  The evolution of the avian genome as revealed by comparative molecular cytogenetics
  Full Text via DOI: 10.1159/000103166 Web of Science: 000249980800009
- 2005
  
  Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?. ASIAN JOURNAL OF ANDROLOGY. 7:419-425.
  Full Text via DOI: 10.1111/j.1745-7262.2005.00068.x Web of Science: 000233829600012
- 2004
  
  The association between male infertility and sperm disomy: Evidence for variation in disomy levels among individuals and a correlation between particular semen parameters and disomy of specific chromosome pairs
  Full Text via DOI: 10.1186/1477-7827-2-82
- 2004
  
  Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. NATURE. 432:695-716.
  Full Text via DOI: 10.1038/nature03154
- 2004
  
  Molecular cytogenetic definition of the chicken genome: The first complete avian karyotype. GENETICS. 166:1367-1373.
  Full Text via DOI: 10.1534/genetics.166.3.1367 Web of Science: 000220950100023
- 2004
  
  The relationship between male infertility and increased levels of sperm disomy
  Full Text via DOI: 10.1159/000079575 Web of Science: 000224244100014
- 2003
  
  Safety issues in assisted reproduction technology - Should men undergoing ICSI be screened for chromosome abnormalities in their sperm?. HUMAN REPRODUCTION. 18:229-235.
  Full Text via DOI: 10.1093/humrep/deg044 Web of Science: 000181040800001
Book Chapter
- 2013
  
  Interphase cytogenetics at the earliest stages of human development. 123-138.
  Full Text via DOI: 10.1007/978-1-4614-6558-4_7
- 2010
  
  Meiotic Recombination and Errors During Spermatogenesis. 357-365.
  Full Text via DOI: 10.1007/978-1-4419-1436-1_22 Web of Science: 000276968200022
Conference
- 2015
  
  Gene repositioning in human lymphocytes following exposure to genotoxic agents. CHROMOSOME RESEARCH. 382-383.
  Web of Science: 000354410600075
- 2015
  
  Male infertility: What role do chromosomes and epigenetic modifications of chromatin play?. CHROMOSOME RESEARCH. 355-356.
  Web of Science: 000354410600026
- 2014
  
  A new arrangement for telomere organisation within the human sperm nucleus: implications for fertilization and the developing embryo. CHROMOSOME RESEARCH. 603-603.
  Web of Science: 000345967900047
- 2014
  
  GLOBAL TELOMERE ORGANISATION IN THE 3D HUMAN SPERM NUCLEUS: A NEW ARRANGEMENT AND INFERENCES FOR FERTILIZATION AND EMBRYOGENESIS.. FERTILITY AND STERILITY. E111-E111.
  Full Text via DOI: 10.1016/j.fertnstert.2014.07.381 Web of Science: 000342500200329
- 2010
  
  Gene density - a determinant of synaptonemal complex length in human males?. HUMAN REPRODUCTION. I147-I148.
  Web of Science: 000279875400360
- 2010
  
  The organisation of the genome in sperm heads of men undergoing chemotherapy for testicular cancer and Hodgkin's lymphoma. HUMAN REPRODUCTION. I71-I71.
  Web of Science: 000279875400173
- 2007
  
  The use of an e-learning constructivist solution in workplace learning. 133-138.
  Full Text via DOI: 10.1145/1362550.1362577
Other Scholarly Work
- 2019
  
  PGDIS Position Statement on the Transfer of Mosaic Embryos 2019. REPRODUCTIVE BIOMEDICINE ONLINE. E1-E4.
  Full Text via DOI: 10.1016/j.rbmo.2019.06.012 Web of Science: 000481591400001
- 2018
  
  Special Issue in Honor of Gordon H. Dixon PREFACE. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 399-402.
  Full Text via DOI: 10.1080/19396368.2018.1532556 Web of Science: 000453409200001
- 2017
  
  Why are we still talking about chromosomal heteromorphisms?. REPRODUCTIVE BIOMEDICINE ONLINE. 1-2.
  Full Text via DOI: 10.1016/j.rbmo.2017.05.006 Web of Science: 000407005000002
- 2017
  
  Introduction and evaluation of case-based learning in the first foundational course of an undergraduate medical curriculum. JOURNAL OF BIOLOGICAL EDUCATION. 295-304.
  Full Text via DOI: 10.1080/00219266.2016.1217909 Web of Science: 000405726500009
- 2013
  
  CLINICAL USE OF SPERM ANEUPLOIDY SCREENING: WHEN IS ENOUGH, ENOUGH?. FERTILITY AND STERILITY. S30-S30.
  Full Text via DOI: 10.1016/j.fertnstert.2013.07.1763 Web of Science: 000342554500097
- 2013
  
  TELOMERE ORGANIZATION WITHIN THE SPERM NUCLEUS: AN ESSENTIAL PREREQUISITE FOR NORMAL FERTILIZATION AND EMBRYOGENESIS?. FERTILITY AND STERILITY. S101-S101.
  Full Text via DOI: 10.1016/j.fertnstert.2013.07.1709 Web of Science: 000342554500328
- 2005
  
  Erratum: Sequence and comparative analysis of the chicken genome provide unique perspective on vertebrate evolution (Nature (2004) 432 (695-716)). NATURE. 777.
  Full Text via DOI: 10.1038/nature03394
Review
- 2021
  
  Genome-wide mapping of genomic DNA damage: methods and implications. CELLULAR AND MOLECULAR LIFE SCIENCES. 6745-6762.
  Full Text via DOI: 10.1007/s00018-021-03923-6 Web of Science: 000691820000001
- 2021
  
  The Impact of SARS-CoV-2 on Sperm Cryostorage, Theoretical or Real Risk?
  Full Text via DOI: 10.3390/medicina57090946 Web of Science: 000700269600001
- 2021
  
  COVID-19 and human reproduction: A pandemic that packs a serious punch. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 3-23.
  Full Text via DOI: 10.1080/19396368.2020.1855271 Web of Science: 000627140200002
- 2019
  
  Meiotic nondisjunction and sperm aneuploidy in humans. R15-R31.
  Full Text via DOI: 10.1530/REP-18-0318 Web of Science: 000456067700002
- 2018
  
  Does genome organization matter in spermatozoa? A refined hypothesis to awaken the silent vessel. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 518-534.
  Full Text via DOI: 10.1080/19396368.2017.1421278 Web of Science: 000453409200009
- 2016
  
  Impact of sperm DNA chromatin in the clinic. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 157-166.
  Full Text via DOI: 10.1007/s10815-015-0624-x Web of Science: 000370774700003
- 2012
  
  Chromosomal disorders and male infertility. ASIAN JOURNAL OF ANDROLOGY. 32-39.
  Full Text via DOI: 10.1038/aja.2011.66 Web of Science: 000298886000005
- 2011
  
  Meiotic recombination errors, the origin of sperm aneuploidy and clinical recommendations. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 93-101.
  Full Text via DOI: 10.3109/19396368.2010.504879 Web of Science: 000286936200013
- 2010
  
  Role of preimplantation genetic diagnosis (PGD) in current infertility practice. 1-10.
  Full Text via DOI: 10.5005/jp-journals-10016-1001
- 2005
  
  The cytogenetics of preimplantation human development: insights provided by traditional and novel techniques. 295-299.
  Full Text via DOI: 10.1007/s00412-005-0340-x Web of Science: 000232712500009
- 2003
  
  The genetic basis of infertility. 13-25.
  Full Text via DOI: 10.1530/rep.0.1260013 Web of Science: 000184160900002

principal investigator on

Gene positioning as a diagnostic and prognostic tool in ovarian cancer awarded by College of Medicine Foundation 2014 - 2017

co-principal investigator on

Grant
- Mass Scale Biosensor Threat Dianostic for In-Theater Defense Utilization awarded by U.S. Army 2010 - 2013

investigator on

Genomic instability, susceptibility to oxidative stress and cellular senescence awarded by Environmental Health Sciences 2017 - 2021

ORCID iD

https://orcid.org/0000-0002-2369-4127 (confirmed)

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