Scholarly & Creative Works
selected scholarly works & creative activities
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Article
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2023Endocrine Disrupting Chemicals Influence Hub Genes Associated with Aggressive Prostate CancerFull Text via DOI: 10.3390/ijms24043191 Web of Science: 000939034100001
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2022Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 148:2881-2891.Full Text via DOI: 10.1007/s00432-022-04026-w Web of Science: 000808418200001
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2022Nuclear respiratory factor 1 transcriptomic signatures as prognostic indicators of recurring aggressive mesenchymal glioblastoma and resistance to therapy in White American females. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 148:1641-1682.Full Text via DOI: 10.1007/s00432-022-03987-2 Web of Science: 000784837600002
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2022Abstract 1442: Discovery of recurrence and prognosis associated genes in prostate cancer. CANCER RESEARCH. 82:1442-1442.Full Text via DOI: 10.1158/1538-7445.am2022-1442
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2022Abstract 779: A NRF1-driven JRK-mediated β-catenin transcriptional activity contributes to the aggressive growth of ovarian cancer. CANCER RESEARCH. 82:779-779.Full Text via DOI: 10.1158/1538-7445.am2022-779
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2022A Better Mechanistic Understanding of Big Data through an Order Search Using Causal Bayesian NetworksFull Text via DOI: 10.3390/bdcc6020056 Web of Science: 000816386200001
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2021Is Mycobacterium tuberculosis carcinogenic to humans?. FASEB JOURNAL. 35.Full Text via DOI: 10.1096/fj.202001581RR Web of Science: 000691122900023
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2021Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosisFull Text via DOI: 10.1016/j.csbj.2021.04.034 Web of Science: 000692620700012
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2020Causal Bayesian gene networks associated with bone, brain and lung metastasis of breast cancer. CLINICAL & EXPERIMENTAL METASTASIS. 37:657-674.Full Text via DOI: 10.1007/s10585-020-10060-0 Web of Science: 000580404900001
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2020Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 146:2777-2815.Full Text via DOI: 10.1007/s00432-020-03320-9 Web of Science: 000551783900003
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2020Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma. MOLECULAR NEUROBIOLOGY. 57:3827-3845.Full Text via DOI: 10.1007/s12035-020-01979-2 Web of Science: 000544199400001
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2018Nuclear Respiratory Factor 1 Acting as an Oncoprotein Drives Estrogen-Induced Breast CarcinogenesisFull Text via DOI: 10.3390/cells7120234 Web of Science: 000455320700012
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2018NRF1 motif sequence-enriched genes involved in ER/PR -ve HER2+ve breast cancer signaling pathways. BREAST CANCER RESEARCH AND TREATMENT. 172:469-485.Full Text via DOI: 10.1007/s10549-018-4905-9 Web of Science: 000447497300021
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2017Environmental estrogen-like endocrine disrupting chemicals and breast cancer. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 457:89-102.Full Text via DOI: 10.1016/j.mce.2016.10.003 Web of Science: 000413128000011
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2017Abstract 938: Estrogen induced NRF1 signaling is a molecular mechanism underlying the generation of different breast cancer stem cell subpopulations leading to intratumoral heterogeneity. CANCER RESEARCH. 77:938-938.Full Text via DOI: 10.1158/1538-7445.am2017-938
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2016Abstract 3312: Transcriptional regulation of chemokine receptor 4 (CXCR4) by nuclear respiratory factor 1 (NRF1) controls estrogen-induced malignant transformation of breast epithelial cells to breast cancer stem cells. CANCER RESEARCH. 76:3312-3312.Full Text via DOI: 10.1158/1538-7445.am2016-3312
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2015Proteomic and Mitochondrial Genomic Analyses of Pediatric Brain Tumors. MOLECULAR NEUROBIOLOGY. 52:1341-1363.Full Text via DOI: 10.1007/s12035-014-8930-3 Web of Science: 000361903400023
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2015Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells. BRITISH JOURNAL OF CANCER. 112:1687-1702.Full Text via DOI: 10.1038/bjc.2014.586 Web of Science: 000354376500009
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2014Bayesian Network and Mechanistic Hierarchical Structure Modeling of Increased likelihood of Developing Intractable Childhood Epilepsy from the Combined Effect of mtDNA Variants, Oxidative Damage, and Copy Number. JOURNAL OF MOLECULAR NEUROSCIENCE. 54:752-766.Full Text via DOI: 10.1007/s12031-014-0364-x Web of Science: 000345995700018
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2013Reverse Engineering of Modified Genes by Bayesian Network Analysis Defines Molecular Determinants Critical to the Development of Glioblastoma. PLOS ONE. 8.Full Text via DOI: 10.1371/journal.pone.0064140 Web of Science: 000321394700034
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2013Discovering gene-environment interactions in Glioblastoma through a comprehensive data integration bioinformatics method. NEUROTOXICOLOGY. 35:1-14.Full Text via DOI: 10.1016/j.neuro.2012.11.001 Web of Science: 000316777200001
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2013Reactive Oxygen Species via Redox Signaling to PI3K/AKT Pathway Contribute to the Malignant Growth of 4-Hydroxy Estradiol-Transformed Mammary Epithelial Cells. PLOS ONE. 8.Full Text via DOI: 10.1371/journal.pone.0054206 Web of Science: 000315186000002
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2008Allelic loss and mutations in a new ETRG-1 gene are early events in diethylstilbestrol-induced renal carcinogenesis in Syrian hamsters. GENE. 408:18-26.Full Text via DOI: 10.1016/j.gene.2007.10.022 Web of Science: 000253033600003
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2007Is In Utero Imprinting of the Brain by Pesticides Involved in Childhood Brain Cancer Development?. EPIDEMIOLOGY. 18:s169-s170.Full Text via DOI: 10.1097/01.ede.0000276854.53888.a7
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2006Development of a self-proliferating Leydig cell line: A hyper-sensitive E-screening model. ONCOLOGY REPORTS. 16:73-77.Web of Science: 000238520400010
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2006SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours. BRITISH JOURNAL OF CANCER. 94:1524-1532.Full Text via DOI: 10.1038/sj.bjc.6603090 Web of Science: 000237648200026
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2006Estrogen exerts a spatial and temporal influence on reactive oxygen species generation that precedes calcium uptake in high-capacity mitochondria: Implications for rapid nongenomic signaling of cell growth. BIOCHEMISTRY. 45:2872-2881.Full Text via DOI: 10.1021/bi051855x Web of Science: 000235792500013
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2006Levels of IL-1 beta control stimulatory/inhibitory growth of cancer cells. FRONTIERS IN BIOSCIENCE. 11:889-898.Full Text via DOI: 10.2741/1845 Web of Science: 000232528000071
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2005Estrogen-induced G(1)/S transition of G(0)-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling. ONCOGENE. 24:4883-4893.Full Text via DOI: 10.1038/sj.onc.1208667 Web of Science: 000230646500002
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2005Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers. BIOCHEMISTRY. 44:6900-6909.Full Text via DOI: 10.1021/bi047629p Web of Science: 000228962500019
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2005Mitochondrial signals to nucleus regulate estrogen-induced cell growth. MEDICAL HYPOTHESES. 64:133-141.Full Text via DOI: 10.1016/j.mehy.2003.12.056 Web of Science: 000225481400031
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2001Occupational exposure to endocrine-disrupting pesticides and the potential for developing hormonal cancers. JOURNAL OF ENVIRONMENTAL HEALTH. 64:17-29.
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2001Identification of novel breast tumor-specific mutation(s) in the q11.2 region of chromosome 17 by RAPD/AP-PCR fingerprinting. GENE. 269:33-43.Full Text via DOI: 10.1016/S0378-1119(01)00458-9
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2001Base sequence-specific attack of stilbene estrogen metabolite(s) on the mitochondrial DNA: implications in the induction of instability in the mitochondrial genome in the kidney of Syrian hamsters.. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 7:389-395.Full Text via DOI: 10.3892/ijmm.7.4.389
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2001The biphasic stimulation of proliferation of Leydig cells by estrogen exposure.. INTERNATIONAL JOURNAL OF ONCOLOGY. 18:623-628.Full Text via DOI: 10.3892/ijo.18.3.623
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1999Detection of mutation(s) or polymorphic loci in the genome of experimental animal and human cancer tissues by RAPD/AP-PCR depend on DNA polymerase. INTERNATIONAL JOURNAL OF ONCOLOGY. 14:753-758.Full Text via DOI: 10.3892/ijo.14.4.753
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1998Concentration dependence of prooxidant and antioxidant properties of catecholestrogens. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 360:105-112.Full Text via DOI: 10.1006/abbi.1998.0934
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1997Estrogen-nucleic acid adducts: Guanine is major site for interaction between 3,4-estrone quinone and COIII gene. CARCINOGENESIS. 18:1247-1249.Full Text via DOI: 10.1093/carcin/18.6.1247
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1997Profound effects of the weak environmental estrogen-like chemical bisphenol A on the growth of the mammary gland of noble rats. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 60:153-160.Full Text via DOI: 10.1016/S0960-0760(96)00130-6
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1996Inhibition of stilbene estrogen-induced cell proliferation of renal epithelial cells through the modulation of insulin-like growth factor-I receptor expression. CANCER LETTERS. 105:51-59.Full Text via DOI: 10.1016/0304-3835(96)04263-2
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1996Stilbene estrogen-mediated enhanced tyrosine phosphorylation of the nuclear protein p53 by nuclear matrix associated tyrosine kinase(s). INTERNATIONAL JOURNAL OF ONCOLOGY. 8:1011-1016.
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1996Up-regulation of nuclear IGF-I receptor by short term exposure of stilbene estrogen, diethylstilbestrol. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 118:1-8.Full Text via DOI: 10.1016/0303-7207(96)03751-3
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1996Biochemical characterization of a mitomycin C-resistant human bladder cancer cell line. INTERNATIONAL JOURNAL OF CANCER. 65:852-857.Full Text via DOI: 10.1002/(SICI)1097-0215(19960315)65:6<852::AID-IJC24>3.0.CO;2-4
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1996Mechanism of antiproliferative activity of luteolin against stilbene-estrogen stimulation of proliferation of hamster renal epithelial cells. INTERNATIONAL JOURNAL OF ONCOLOGY. 9:811-814.Full Text via DOI: 10.3892/ijo.9.4.811
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1995Estrone-induced cell proliferation and differentiation in the mammary gland of the female noble rat. CARCINOGENESIS. 16:1955-1961.Full Text via DOI: 10.1093/carcin/16.8.1955
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1995Perturbation of cell cycle kinetics in the mammary gland by stilbene estrogen, diethylstilbestrol (DES). CANCER LETTERS. 94:55-63.Full Text via DOI: 10.1016/0304-3835(95)03824-G
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1995Activation of phosphorylation of plasma membrane insulin-like growth factor-i receptors in the kidney of syrian hamsters by diethylstilbestrol. CARCINOGENESIS. 16:1339-1344.Full Text via DOI: 10.1093/carcin/16.6.1339
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1995Organ-specific inhibition of types I,II and III transcriptional activity in hamsters exposed to stilbene estrogen. CARCINOGENESIS. 16:1017-1021.Full Text via DOI: 10.1093/carcin/16.5.1017
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1995In vivo binding of diethylstilbestrol to nuclear proteins of kidneys of Syrian hamsters. CANCER LETTERS. 90:215-224.Full Text via DOI: 10.1016/0304-3835(95)03706-3
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1995Phosphorylation of Tyrosine Residues of RNA Polymerase II and Other Nuclear Proteins by Active Chromatin Tyrosin Kinase(s). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 209:356-364.Full Text via DOI: 10.1006/bbrc.1995.1511
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1995Mitochondrial enzyme-catalyzed oxidation and reduction reactions of stilbene estrogen. CARCINOGENESIS. 16:891-895.Full Text via DOI: 10.1093/carcin/16.4.891
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1995In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 210:424-433.Full Text via DOI: 10.1006/bbrc.1995.1678
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1995In vivo DNA adduct formation by bisphenol A. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 26:60-66.Full Text via DOI: 10.1002/em.2850260109
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1995The antiproliferative effect of luteolin against diethylstilbestrol-induced cell proliferation in the mammary gland of rat. INTERNATIONAL JOURNAL OF ONCOLOGY. 7:1361-1366.Full Text via DOI: 10.3892/ijo.7.6.1361
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1994Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin. CANCER LETTERS. 87:85-89.Full Text via DOI: 10.1016/0304-3835(94)90413-8
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1994Sex hormone-induced nuclear DNA damage and lipid peroxidation in the dorsolaterel prostates of Noble rats. CANCER LETTERS. 84:155-162.Full Text via DOI: 10.1016/0304-3835(94)90370-0
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1994Catalysis of the oxidation and reduction reactions of steroid and stilbene estrogens by nuclear enzymes. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 315:310-316.Full Text via DOI: 10.1006/abbi.1994.1505
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1992Examination of microsomal cytochrome P450-catalyzed in vitro activation of O-phenylphenol to DNA binding metabolite(s) by P-postlabeling technique. CARCINOGENESIS. 13:1593-1597.Full Text via DOI: 10.1093/carcin/13.9.1593
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1992Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the β-naphthoflavone-inducible cytochrome P450 IA family. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 296:450-456.Full Text via DOI: 10.1016/0003-9861(92)90596-O
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1992Enhanced expression of membrane phosphoproteins tyrosine phosphorylation in estrogen-induced kidney tumors. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 186:228-236.Full Text via DOI: 10.1016/S0006-291X(05)80797-1
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1992Lack of effectiveness of antiestrogens RU 39,411 or keoxifene in the prevention of estrogen-induced tumors in Syrian hamsters. CANCER LETTERS. 64:23-29.Full Text via DOI: 10.1016/0304-3835(92)90017-P
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1992Elevation of protooncogene messenger RNAs in estrogen-induced kidney tumors in the hamster. CARCINOGENESIS. 13:601-604.Full Text via DOI: 10.1093/carcin/13.4.601
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1992
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1991Xanthine oxidase-catalyzed reduction of estrogen quinones to semiquinones and hydroquinones. BIOCHEMICAL PHARMACOLOGY. 42:1627-1631.Full Text via DOI: 10.1016/0006-2952(91)90433-6
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1991Cytochrome b
5 -mediated redox cycling of estrogen. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 285:331-338.Full Text via DOI: 10.1016/0003-9861(91)90368-S -
1990Inhibition of estrogen-induced kidney carcinogenesis in syrian hamsters by modulators of estrogen metabolism. CARCINOGENESIS. 11:567-570.Full Text via DOI: 10.1093/carcin/11.4.567
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1990The O6-methylation of 4-hydroxyestradiol is inhibited by 2-hydroxyestradiol: Implications for estrogen-induced carcinogenesis. CARCINOGENESIS. 11:459-462.Full Text via DOI: 10.1093/carcin/11.3.459
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1990Covalent binding of phenytoin to protein and modulation of phenytoin metabolism by thiols in A/J mouse liver microsomes. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 252:895-900.
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1990Cytochrome b5 mediated redox cycling of estrogens. FREE RADICAL BIOLOGY AND MEDICINE. 9:33.Full Text via DOI: 10.1016/0891-5849(90)90286-r
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1989Mechanism of inhibition of estrogen-induced renal carcinogenesis in male syrian hamsters by vitamin C. CARCINOGENESIS. 10:1983-1988.Full Text via DOI: 10.1093/carcin/10.11.1983
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1989Metabolic oxidation of diethylstilbestrol to diethylstilbestrol-4', 4"-quinone in syrian hamsters. CARCINOGENESIS. 10:1241-1245.Full Text via DOI: 10.1093/carcin/10.7.1241
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1989Changes in Activities of Free Radical Detoxifying Enzymes in Kidneys of Male Syrian Hamsters Treated with Estradiol. CANCER RESEARCH. 49:1475-1480.
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1988Age-related change in the multiple unit activity of the rat brain parietal cortex and the effect of centrophenoxine. EXPERIMENTAL GERONTOLOGY. 23:161-174.Full Text via DOI: 10.1016/0531-5565(88)90003-4
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1988Characterization of drug metabolism enzymes in estrogen-induced kidney tumors in male syrian hamsters. CANCER RESEARCH. 48:5726-5729.
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1988Temporary decrease in renal quinone reductase activity induced by chronic administration of estradiol to male Syrian hamsters. Increased superoxide formation by redox cycling of estrogen. JOURNAL OF BIOLOGICAL CHEMISTRY. 263:3646-3651.
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1987SHUNTING OF PHENYTOIN IN VITRO METABOLIC ACTIVATION BY GLUTATHIONE TO LESS REACTIVE METABOLITES: ANIMAL AND HUMAN FETAL TISSUE. PEDIATRIC RESEARCH. 21:242-242.Full Text via DOI: 10.1203/00006450-198704010-00447
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1984Effects of Chlorpromazine on the Activities of Antioxidant Enzymes and Lipid Peroxidation in the Various Regions of Aging Rat Brain. JOURNAL OF NEUROCHEMISTRY. 42:628-633.Full Text via DOI: 10.1111/j.1471-4159.1984.tb02728.x
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1983Effect of centrophenoxine on the antioxidative enzymes in various regions of the aging rat brain. EXPERIMENTAL GERONTOLOGY. 18:185-197.Full Text via DOI: 10.1016/0531-5565(83)90031-1
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Book
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2010Environmental factors, genes, and the development of human cancersFull Text via DOI: 10.1007/978-1-4419-6752-7
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2010Environmental Factors, Genes, and the Development of Human Cancers IntroductionFull Text via DOI: 10.1007/978-1-4419-6752-7_1 Web of Science: 000282535900001
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Book Chapter
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2022Environmental DNA insights in search of novel genes/taxa for production of biofuels and biomaterials. 111-135.Full Text via DOI: 10.1016/B978-0-12-823500-3.00015-7
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2022Epigenome's environmental sensitivity and its impact on health. 451-478.Full Text via DOI: 10.1016/B978-0-12-823500-3.00009-1
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2019Malformations of cortical development and epilepsy in children. 211-218.Full Text via DOI: 10.1016/B978-0-12-409548-9.11744-0
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2011Environment, Genetic and Epigenetic Alterations and Pediatric Central Nervous System Tumors. 559-568.Full Text via DOI: 10.1016/B978-0-444-52272-6.00071-4
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2011Malformations of Cortical Development and Epilepsy in Children. 595-602.Full Text via DOI: 10.1016/B978-0-444-52272-6.00073-8
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2010Approaches to Identify Environmental and Epigenomic Components or Covariates of Cancer and Disease Susceptibility. 197-219.Full Text via DOI: 10.1007/978-1-4419-6752-7_8 Web of Science: 000282535900008
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2010Gene-Environment Interaction and Susceptibility to Pediatric Brain Tumors. 223-252.Full Text via DOI: 10.1007/978-1-4419-6752-7_9 Web of Science: 000282535900009
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2005Estrogen-Induced Mutations and Its Role in the Development of Tumorigenesis. 475-479.Full Text via DOI: 10.1007/0-387-23761-5_51
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1998Pro-Oxidant and Antioxidant Effects of Estrogens. 425-435.Full Text via DOI: 10.1385/0-89603-472-0:425
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Conference
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2020Aberrant transcription factor activity of NRF1, NFE2L2, E2F1, RFX1, and MEF2 associated with severity of astrocytoma. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2020-4391 Web of Science: 000590059301273
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2019Abstract 2441: Association between NRF1 regulatory gene networks and cancer and aging. 2441-2441.Full Text via DOI: 10.1158/1538-7445.sabcs18-2441
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2019Association between NRF1 regulatory gene networks and cancer and aging. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2019-2441 Web of Science: 000488279400400
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2018Exosomal ID3 is pro-metastatic through guiding NRF1-induced breast cancer stem cells across the blood-brain-barrier. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2018-1128 Web of Science: 000468818903101
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2018Identifying the regulatory network structure of the genes involved in signaling pathways underlying ER-PR-HER2+breast cancer using Bayesian modeling of genome-wide NRF1 DNA motif sequence-enriched genes. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2018-4274 Web of Science: 000468819502469
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2018Role of NRF1 regulatory gene-networks in glioblastoma. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2018-1127 Web of Science: 000468818903100
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2017Abstract 1552: Integrative bioinformatics analyses of ChIP seq and RNA seq data reveals a complex regulatory landscape of NRF1 network involved in the pathogenesis of breast cancer. CANCER RESEARCH. 1552-1552.Full Text via DOI: 10.1158/1538-7445.am2017-1552
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2016Abstract 3322: Estrogen and nuclear respiratory factor 1 act as joint mediators of redox modulation and stem cell aging that contribute in the pathogenesis of breast cancer. CANCER RESEARCH. 3322-3322.Full Text via DOI: 10.1158/1538-7445.am2016-3322
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2015Overexpression of NRF1 leads to the generation of cancer stem-like cells and resistance to anoikis _ pathways to anchorage-independent growth during estrogen-induced malignant transformation. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2015-803 Web of Science: 000371578501256
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2015Phosphodeficient NRF1 mutant suppresses the susceptibility of the breast epithelial cells to develop tumors when exposed to estrogen - a major breast cancer risk factor. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2015-4559 Web of Science: 000371597104187
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2014Redox signaling to nuclear respiratory factor-1 proteins by reactive oxygen species contributes to the estrogen-induced breast tumor development. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2014-3179 Web of Science: 000349910200183
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2012Novel 4-N-modified gemcitabine analogs. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Web of Science: 000324503201668
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2011Estrogen-induced redox signaling via NRF-1 is involved in the development of breast cancer. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2011-LB-12 Web of Science: 000209701305418
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2011Identifying gene alterations required for the development of astrocytoma. 1037-1041.Web of Science: 000314989301008
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2010Abstract 5050: Functional characterization of a newly identified growth regulatory gene SKCG-1 in human kidney cancer. CANCER RESEARCH. 5050-5050.Full Text via DOI: 10.1158/1538-7445.am10-5050
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2010Abstract 604: Erucin treatment through induction of thioredoxin reductase may alter tamoxifen resistance in LCC2 cells. CANCER RESEARCH. 604-604.Full Text via DOI: 10.1158/1538-7445.am10-604
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2009Redox Status Contributes to Tamoxifen-Resistant Growth of Breast Cancer.. CANCER RESEARCH. 810S-810S.Web of Science: 000272920702093
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2009NRF-1 signaling participates in the estrogen-mediated growth of breast cancer cells.. CANCER RESEARCH.Web of Science: 000209701803459
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2007
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2007
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2007General remarks. 33-35.
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2007Is in utero imprinting of the brain by pesticides involved in childhood brain cancer development?. EPIDEMIOLOGY. S169-S170.Web of Science: 000249018300556
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20074-OH-E2-induced oxidants through NRF-1 controls transcription of G1-S and G2-M phase cell cycle genes. FEBS JOURNAL. 179-179.Web of Science: 000253283800541
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2006Estrogen-induced ROS signaling molecules and their role in brain cancer. CANCER RESEARCH.Web of Science: 000454608801202
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Note
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2005Carcinogenicity of combined oestrogen-progestagen contraceptives and menopausal treatment. LANCET ONCOLOGY. 552-553.Full Text via DOI: 10.1016/S1470-2045(05)70273-4
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Other Scholarly Work
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2016Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 741-745.Full Text via DOI: 10.1136/jech-2015-207005 Web of Science: 000380152600002
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2016Origanum majorana organic extract induces senescence and autophagic cell death in breast cancer cells through influencing mitochondrial metabolism. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2016-4061 Web of Science: 000389969803034
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2016Association between serum concentrations of polychlorinated biphenyls (PCBs) and increased risk of breast cancer among US women. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.AM2016-3433 Web of Science: 000389940604187
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2010Differential role of estrogen receptor positive NRF1(High) and NRF1(Low) cells in breast cancer development and progression. NEW BIOTECHNOLOGY. S25-S25.Full Text via DOI: 10.1016/j.nbt.2010.01.021 Web of Science: 000209825000061
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2001Stilbene estrogen produces higher levels of mitochondrial DNA adducts than nuclear DNA adducts in the target organ of cancer (liver) of male Sprague Dawley rats.. ONCOLOGY REPORTS. 1035-1038.Full Text via DOI: 10.3892/or.8.5.1035
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1993Insulin-like growth factor 1 receptors are increased in estrogen-induced kidney tumors.. CANCER RESEARCH. 2256-2259.
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Preprint
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Review
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2018Interplay between NRF1, E2F4 and MYC transcription factors regulating common target genes contributes to cancer development and progression. 465-484.Full Text via DOI: 10.1007/s13402-018-0395-3 Web of Science: 000444812800001
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2016Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.Full Text via DOI: 10.3390/ijms17122086 Web of Science: 000392280500130
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2013Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. 60-79.Full Text via DOI: 10.1016/j.bbcan.2013.02.005 Web of Science: 000320475800006
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2011Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. 115-133.Full Text via DOI: 10.1016/j.bbcan.2010.10.005 Web of Science: 000287124400009
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2007Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS. 235-257.Full Text via DOI: 10.1080/15287390600974924 Web of Science: 000247875600001
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2007Signature of mitochondria of steroidal hormones-dependent normal and cancer cells: Potential molecular targets for cancer therapy. FRONTIERS IN BIOSCIENCE. 154-173.Full Text via DOI: 10.2741/2056 Web of Science: 000243745000013
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2005Estrogen, mitochondria, and growth of cancer and non-cancer cellsFull Text via DOI: 10.1186/1477-3163-4-1
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2004Genetics and bioenergetics of mitochondria influencing the etiology and pharmacology of steroidal hormones. 379-390.Full Text via DOI: 10.2174/1570160043377295
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2004Estrogen-induced genetic alterations and their role in carcinogenicity. 245-257.Full Text via DOI: 10.2174/1389202043349471
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2000Estrogens as endogenous genotoxic agents--DNA adducts and mutations.. 75-93.Full Text via DOI: 10.1093/oxfordjournals.jncimonographs.a024247
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1990Free radical generation by redox cycling of estrogens. FREE RADICAL BIOLOGY AND MEDICINE. 415-423.Full Text via DOI: 10.1016/0891-5849(90)90108-U
Works By Students
chaired theses and dissertations
- Doke, Mayur Arvind, The Role of ID3 and PCB153 in the Hyperproliferation and Dysregulation of Lung Endothelial Cells 2018
- Preciados, Mark, Exposure to Estrogenic Endocrine Disrupting Chemicals and Brain Health 2018
- Morgan, Marisa L, Exposure to Endocrine Disrupting Compounds and Reproductive Toxicity in Women 2014
- Garba, Nana Aisha, The Role of Redox Signaling in the Molecular Mechanism of Tamoxifen Resistance in Breast Cancer 2012
- Kunkle, Brian W, The Potential Role of Environmental Exposures and Genomic Signaling in Development of Central Nervous System Tumors 2011
- Luna, Brenda, Prenatal Environmental Exposure and Neurodevelopmentally Important Gene Expression in Malformed Brain Tissue from Pediatric Intractable Epilepsy Patients 2011
- Penney, Rosalind B, Thioredoxin and Jab1 Control Estrogen- and Antiestrogen-Mediated Progression of the Cell Cycle Through p27 Interactions 2011
- Okoh, Victor, 4-Hydroxy Estradiol-Induced Oxidant-Mediated Signaling Is Involved In The Development Of Breast Cancer 2010
Research
principal investigator on
- Estrogen-Induced Breast Cancer Pathogenesis awarded by U.S. Department of Veterans Affairs 2014 - 2018
- Role of Estrogen-Induced Breast Cancer Pathogenesis awarded by U.S. Department of Veterans Affairs 2013 - 2015
- Identification of the Mechanisms Underlying Antiestrogen Resistance: Breast Cancer Research Partnership between FIU - UM Braman Family Breast Cancer Institute. awarded by U.S. Department of Defense 2007 - 2012
- Inhibition of Estrogen-Induced Growth of Breast Cancer by Targeting Mitochondria. awarded by Army Research Office 2007 - 2010
co-principal investigator on
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Grant
investigator on
Identifiers
ORCID iD
- https://orcid.org/0000-0001-6409-1341 (confirmed)
visualizations
publication subject areas
- Biochemistry & Molecular Biology
- Biophysics
- Cell Biology
- Chemistry
- Endocrinology & Metabolism
- Environmental Sciences & Ecology
- Genetics & Heredity
- Neurosciences & Neurology
- Oncology
- Pathology
- Pharmacology & Pharmacy
- Public, Environmental & Occupational Health
- Science & Technology - Other Topics
- Toxicology