FIU Discovery

Hypersialylation of Tumor Cells Promotes Pancreatic Cancer Progression.  The FASEB Journal.  36.

ST6Gal1 Contributes to Pancreatic Cancer Initiation by Promoting Pancreatitis-Induced Acinar to Ductal Metaplasia.  The FASEB Journal.  36.

STEM-08. ST6Gal1-MEDIATED SILALYLATION IS CRITICAL FOR GLIOBLASTOMA GROWTH.  Neuro-Oncology.  23:vi22-vi22.

Galectin-9 bridges human B cells to vascular endothelium while programming regulatory pathways.  Journal of Autoimmunity.  117.

Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover.  Journal of Biological Chemistry.  295:14153-14163.

Sa1210 ST6GAL-I IS UPREGULATED IN BARRETT'S ESOPHAGUS STEM CELLS AND DYSPLASIA.  Gastroenterology.  158:s-313.

156 – H. Pylori Induces Gastric Epithelial Cell Expression of Glycosyltransferase St6Gal-I in the Pathogenesis of Gastric Adenocarcinoma.  Gastroenterology.  156:s-36-s-37.

283 – The Role of St6Gal-I, a Glycosyltransferase Strongly Associated with Mucosal Carcinogenesis, in Barrett's Esophagus and Esophageal Adenocarcinoma.  Gastroenterology.  156:s-57.

Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis.  Stem Cells.  37:453-462.

716 - Glycosyltransferase ST6GAL-I Associates with WNT Signaling Molecules and is a Characteristic Marker of Mucosal Epithelial Stem Cells.  Gastroenterology.  154:s-148-s-149.

Sa1102 - Barrett's Epithelium Displays Increased Expression of St6Gal-I, a Glycosyltransferase Strongly Associated with Mucosal Carcinogenesis.  Gastroenterology.  154:s-241.

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.  Journal of Biological Chemistry.  293:984-994.

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.  Cancer Research.  76:3978-3988.

Study of the thermo-oxidative degradation behavior of isotactic polypropylene with the varying ethylene content.  Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry.  46:1198-1202.

Studies on thermo-oxidative degradation behavior of isotactic polypropylene on ethylene incorporation.  JOURNAL OF POLYMER MATERIALS.  20:343-349.

Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.  Journal of Biological Chemistry.  296.

Microenvironmental and intracellular galectin-3 govern melanoma progression.  Glycobiology. 1689-1689.

ST6Gal1 promotes acinar to ductal metaplasia and pancreatic cancer progression.  Glycobiology. 1688-1688.

hypoxia controls the glycobiological signature and related pro-tumorigenic properties of metastatic melanomas.  Glycobiology. 1683-1684.

Abstract 2609: Hypoxia-mediated downregulation of GCNT2/I-antigen in metastatic melanoma accelerates disease progression and mortality.  Cancer Research. 2609-2609.

Hypoxia-mediated downregulation of GCNT2/I-antigen in metastatic melanoma accelerates disease progression and mortality..  Cancer Research.

GCNT2 suppression in metastatic melanoma is potentiated by hypoxia and correlates with aggressive disease progression.  Glycobiology. 1041-1041.

Galectin-9 helps govern human B cell adhesion to and migration through human vascular endothelium..  Glycobiology. 1071-1071.

High expression of ST6Gal-I promotes a stem-like phenotype in pancreatic epithelial cells.  Glycobiology. 1112-1112.

Abstract 4092: Glycosyltransferase ST6Gal-I promotes pancreatic ductal adenocarcinoma progression and metastasis.  Cancer Research. 4092-4092.

Abstract 2114: Glycosyltransferase ST6Gal-I protects against chemotherapy induced DNA damage and subsequent apoptosis in pancreatic adenocarcinoma cells.  Cancer Research. 2114-2114.

Abstract 3327: The tumor associated sialyltransferase ST6Gal-I promotes a cancer stem cell phenotype and upregulates stem-related transcription factors.  Cancer Research. 3327-3327.

Analysis of Galectin-Binding Receptors on B Cells.  Methods in molecular biology (Clifton, N.J.). 565-580.

Cancer immunotherapy needs to learn how to stick to its guns.  Journal of Clinical Investigation. 5089-5091.

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

Melanoma-associated glycosyltransferase GCNT2 as an emerging biomarker and therapeutic target.  British Journal of Dermatology. 294-301.