Hanadys Ale, MD, FAAAAI, is an Assistant Professor at the Florida International University Herbert Wertheim College of Medicine and an allergist and immunologist who cares for children and adults at Joe DiMaggio Childrenâs Hospital and Memorial Healthcare System. As Medical Director of the 22q Multidisciplinary Program, she leads pediatric and adult clinics for individuals with 22q11.2 deletion syndrome, with a focus on continuity of care from childhood into adulthood. She also chairs the Network of the Americas of the 22q11.2 Society.
Dr. Ale directs the immunology unit for first-year FIU medical students and serves as Program Director of the Transitional Year Residency Program at Memorial Healthcare System. A member of FIUâs inaugural medical school class, she graduated with honors in 2013 and was inducted into Alpha Omega Alpha. She completed her pediatrics residency at Nicklaus Childrenâs Hospital and her allergy and immunology fellowship through Nicklaus Childrenâs Hospital and Cleveland Clinic Florida. FIU recognized her with the 2018 Distinguished Alumna Torch Award and the 2025 Large Group Teaching Award.
research interests
Dr. Ale’s research focuses on inborn errors of immunity, with an emphasis on the clinical and immunologic features of 22q11.2 deletion syndrome across the lifespan. Her work examines antibody function and vaccine responses, including responses to pneumococcal vaccination, as well as the broader clinical manifestations of the syndrome. She is particularly interested in how detailed characterization of these features can guide individualized monitoring and care as patients transition from pediatric to adult services. She collaborates with investigators across institutions to characterize the variability of 22q11.2 deletion syndrome and study how its clinical and immunologic features evolve over time. Her work has appeared in The Journal of Allergy and Clinical Immunology: In Practice, Journal of Clinical Immunology, and Pediatrics in Review.